Guildford, UK, 15 June 2012:  ReNeuron announces that, following yesterday’s announcement of interim Phase I clinical data with its ReN001 stem cell therapy for disabled stroke patients, the Company is also presenting further positive pre-clinical data across its other therapeutic programmes at the 10th Annual Meeting of the International Society for Stem Cell Research in Yokohama, Japan, running from 13-16 June 2012. 

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Guildford, UK, 14 June 2012:  ReNeuron is pleased to announce the presentation of interim data from the PISCES (Pilot Investigation of Stem Cells in Stroke) clinical trial of its ReN001 stem cell therapy for disabled stroke patients.

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Guildford, UK, 21 May 2012:  ReNeuron announces that its Chief Executive Officer, Michael Hunt, will present to delegates today at the World Stem Cells & Regenerative Medicine Conference in London.

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Guildford, UK, 16 May 2012:  ReNeuron announces that it has signed a new cell manufacturing contract with Angel Biotechnology Holdings plc (AIM:ABH), a biopharmaceutical contract manufacturer, to perform GMP drug product manufacturing services to serve the remaining part of the PISCES Phase I clinical trial of ReNeuron’s ReN001 stem cell therapy for stroke.

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Guildford, UK, 3 May 2012: On 3 April 2012, the Board of ReNeuron Group plc announced the details of a Placing and Open Offer.

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Guildford, UK, 27 April 2012:  On 3 April 2012, the Board of ReNeuron Group plc announced the details of a Placing and Open Offer.

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Guildford, UK, 7 August 2013: ReNeuron announced on 22 July 2013 the details of a Placing in which it had conditionally raised proceeds of £25.35 million before expenses.

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The Board is pleased to announce that today, at a General Meeting of the Company, shareholders approved all the resolutions by the relevant majorities.  Therefore, the Placing is now unconditional, save for the admission of the new Ordinary Shares.

The Company has applied for admission to trading on AIM for both the 29,033,000 new Ordinary Shares to be issued to VCT/EIS investors (the “First Admission”) and the 984,967,000 new Ordinary Shares to be issued to non-VCT/EIS investors (the “Second Admission”). It is expected that First Admission will become effective and dealings will commence at 8.00 a.m. on 8 August 2013 and that the Second Admission will become effective and dealings will commence at 8.00 a.m. on 9 August 2013.

In addition, certain Directors subscribed for new Ordinary Shares pursuant to the Placing. The resultant shareholding of each Director is outlined below.

  1. Director                Current shareholding Number of Placing Shares  % holding after Second Admission

Bryan Morton         215,909                  800,000                            0.057%
Michael Hunt          453,023                  800,000                            0.070%
Dr. John Sinden    1,611,902                 600,000                            0.124%
John Berriman        125,000                  600,000                            0.041%
Simon Cartmell       187,000                 600,000                            0.044%
Mark Docherty        344,859                 600,000                            0.053%
Dr. Paul Harper       251,709                 200,000                            0.025%
Dr. Tim Corn          nil                          200,000                            0.011%

Following Second Admission, the Company will have 1,788,827,700 Ordinary Shares in issue, all with voting rights. The Company holds no Ordinary Shares in treasury. The total number of current voting rights in the Company will therefore be 1,788,827,700 shares.

The above figure (1,788,827,700 Ordinary Shares) may be used by shareholders as the denominator for the calculation by which they will determine if they are required to notify their interest in, or a change in their interest in, the Company under the FCA’s Disclosure and Transparency Rules.

In addition, the Company confirms that Sir Chris Evans will be appointed as a non-executive director of the Company effective on completion of Second Admission.

Capitalised terms in this announcement have the same meaning as in the announcement of 22 July 2013 except where otherwise indicated.

Enquiries:

  1. ReNeuron        +44 (0) 1483 302560
    Michael Hunt, Chief Executive Officer
    Pat Huggins, Head of Finance
  2. Buchanan        +44 (0) 20 7466 5000
    Mark Court, Fiona Henson, Sophie Cowles

Cenkos Securities       +44 (0) 20 7397 8900
Stephen Keys, Adrian Hargrave (NOMAD and Broker)
Andy Roberts (Sales)

About ReNeuron

ReNeuron is a leading, clinical-stage stem cell business.  Its primary objective is the development of novel stem cell therapies targeting areas of significant unmet or poorly met medical need. 

ReNeuron has used its unique stem cell technologies to develop cell-based therapies for significant disease conditions where the cells can be readily administered “off-the-shelf” to any eligible patient without the need for additional immunosuppressive drug treatments.  ReNeuron’s lead candidate is its ReN001 stem cell therapy for the treatment of patients left disabled by the effects of a stroke. This therapy is currently in clinical development.  The Company is also developing stem cell therapies for other conditions such as critical limb ischaemia, a serious and common side-effect of diabetes, and blindness-causing diseases of the retina such as retinitis pigmentosa.

ReNeuron has also developed a range of stem cell lines for non-therapeutic applications – its ReNcell® products for use in academic and commercial research.  The Company’s ReNcell®CX and ReNcell®VM neural cell lines are marketed worldwide under license by USA-based Merck Millipore.

ReNeuron’s shares are traded on the London AIM market under the symbol RENE.L.  Further information on ReNeuron and its products can be found at www.reneuron.com.

Guildford, UK, 20 April 2012: ReNeuron announces that it will be participating in the Master Investor 2012 investment conference, to be held at the Business Design Centre in London on 21 April.

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Guildford, UK, 3 April 2012: ReNeuron is pleased to announce a firm Placing, together with an Open Offer to existing shareholders, to raise up to £9.4 million, before expenses.

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Guildford, UK, 30 March 2012: ReNeuron announces that the Company has approved the issue of 187,784 ordinary shares of 1p each in the capital of the Company (“Shares”) at a price of 5.025p per Share (being the mid-market closing price as at 28 March 2012) pursuant to an incentive agreement with one of its research consultants.

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