The Directors (together with their families and their family trusts and pension scheme arrangements) in aggregate hold 31,256,631 ordinary shares in the Company, representing 0.99% of the Company’s current issued share capital.

36.47% of the issued share capital is not in public hands.

The Company is aware of the following significant (3% or greater) shareholdings in the Company’s ordinary shares:

Number of ordinary shares % of issued share capital
Woodford Investment Management LLP 35.48%
Wales Life Sciences Investment Fund LP 9.50%
Invesco Limited 9.25%
Aviva plc & its subsidiaries 6.34%

The above information was last updated on Tuesday, 01 September 2015