We have used our unique stem cell technologies to develop cell-based therapies for significant disease conditions where the cells can be readily administered “off-the-shelf” to any eligible patient without the need for additional drug treatments. Our lead stem cell therapeutic candidate is a therapy for the treatment of patients left disabled by a stroke. We have announced positive Phase II data with this therapeutic candidate and are pursuing plans to commence a Phase IIb trial in patients who are living with disability post-stroke.
Our hRPC stem cell candidate is being developed for the treatment of retinal diseases. Clinical development of this candidate in retinitis pigmentosa, a blindness-causing disease of the retina, has commenced in the US and we are expanding our hRPC programme to target a further retinal disease, cone-rod dystrophy.
We are also progressing pre-clinical development of our exosome nanomedicine platform. Exosomes are nanoparticles secreted into the culture media during the expansion of our stem cells. They contain a number of biologically active molecules such as proteins and microRNAs (miRNAs) which are short, non-coding RNAs that can regulate gene expression. These molecules may have potential therapeutic benefits across a number of disease areas.
Our principal strategy is to gain clinical validation for our cell therapy programmes via well-designed clinical trials in well-regulated territories. Ultimately, we expect to realise value for our technologies and therapeutic programmes via out-license to commercial development partners at the appropriate points in their development. In order to achieve these objectives, we work closely with a number of key academic and industrial partners while continuing to maintain tight control over our financial resources.
To view the latest corporate presentation please click here.
ReNeuron is incorporated in and operates primarily in the UK. Our shares are traded on the London AIM market under the symbol RENE.L