Open label prospective study of the safety and tolerability of the human retinal progenitor cell (hRPC) therapy candidate in the treatment of patients with retinitis pigmentosa.

Clinical Trial Stage: Phase I/IIa

Trial Purpose: To evaluate the safety, tolerability and preliminary efficacy of sub-retinally transplanted hRPCs in patients with advanced retinitis pigmentosa.

Status: Phase IIa is being expanded; data expected during 2021


Randomised, placebo-controlled study of efficacy and safety of CTX cells in subjects with disability following ischaemic stroke (PISCES III).

Clinical Trial Stage: Phase IIb

Trial Purpose: To assess the efficacy of intracerebral CTX0E03 DP by change in degree of dependency and disability from baseline, as measured by modified Rankin Score (mRS).

Status : Recruitment in the US suspended


Efficacy study of CTX cells in patients with stable paresis of the arm following an ischaemic stroke (PISCES II).

Clinical Trial Stage: Phase IIa

Trial Purpose: To determine if treatment at a dose of 20m cells improves recovery in use of paretic arm in stroke patients to justify a larger pivotal study

Status : Study completed


Safety study of CTX cells in the treatment of patients with stable ischaemic stroke (PISCES I).

Clinical Trial Stage: Phase I

Trial Purpose: To test safety of CTX cells delivered by injection into the damaged brains of male patients > 60 left moderately to severely disabled 6 months to 5 years following an ischaemic stroke

Status : Data reported


Non-interventional, observational study for patients with stable ischaemic stroke to document clinical course and establish pool of patients for on-going trials.

Clinical Trial Stage: Observational

Trial Purpose: To build data set in untreated disabled stroke patients and facilitate on-going clinical trials

Status: Study completed


Further information regarding our clinical trials, including relevant contact details, may be found on clinicaltrials.gov, a registry of clinical trials providing patients, family members, and members of the public free and easy access to information on clinical studies for a wide range of diseases and conditions: please click here.